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 Roles turned down by Owen Wilson:

Ocean's Eleven
Owen & Luke Wilson were set to play the Malloy brothers but dropped out. The roles went to Casey Affleck and Scott Caan.

There's Something About Mary
Initially, the studio was reluctant to cast Ben Stiller and the Farrelly brothers were said to have chosen Wilson instead. The studio was even more reluctant about this choice, so they went back to Stiller.
Actor who got the part: Ben Stiller

Tropic Thunder
Owen Wilson was set to film a cameo but dropped out after being hospitalized for an attempted suicide.
Actor who got the part: Matthew McConaughey

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