Anderson was considered to play Clarice after Jodie Foster declined.

Considered to take on the role of Clarice in Hannibal.

Demme turned down a chance to direct the sequel to his Oscar-winning film "The Silence of the Lambs."

Foster refused to reprise her Oscar-winning role of Clarice Starling due to concerns about how the character was written in "Hannibal."

Helen Hunt was considered to play Clarice after Jodie Foster declined.

According to The London Daily Telegraph, Angelina Jolie was one of the acctresses considered for the role of Clarice when Jodie Foster refused the part.

One of the many actresses considered when Jodie Foster refused to reprise her role as "Clarice Starling."

John Malkovich was reportedly contacted about playing Lector if Hopkins didn't want to play the part.

Christopher Reeve turned down the role of Verger.

Tim Roth was considered to play the title role when Hopkins expressed doubt in reprising the role.